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| Posted : Oct, 2006 | Dust mites disrupt skin's protective function, causing severe skin diseases | ||||||||||||||||||||||||||||||||
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A research in Japan found that dust mites and their droppings contain an enzyme, which damages the skin's protective function, making it vulnerable to attack by other allergens or pathogens. Many patients only go to the hospital for treatment after they have developed severe skin diseases, without knowing why. In the research, the scientists dabbed hairless mice with solution containing the dust mite enzyme. They observed that the rodents soon suffered water loss on their skins, which is an indication of disruption of the skin barrier. The scientists then dabbed the mice with riboflavin - or vitamin B2 - which is a substitute for allergens and irritants in the environment. The penetration of riboflavin into the skin was observed. This indicated that allergens and other irritants can penetrate the skin after the dust mites disrupt the skin barrier function. In a healthy person, the skin barrier is effective in fending off irritants. |
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